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#Biafine emulsion skin
Biafine is liberally applied to the skin and covered with a dressing, such as gauze. Find patient medical information for Biafine Emulsion topical on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Since autolytic debridement is the preferred method for removing dead and scarred tissue, moist dressings are needed and must be changed daily. Wound and burn management involve methods to enhance tissue regeneration and to minimize infection during the healing process.
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#Biafine emulsion full
According to the Biafine package insert, the FDA has approved Biafine for use in full thickness wounds, pressure sores and dermal ulcers (includes lower leg ulcers), superficial wounds, first- and second-degree burns, sunburns, dermal donor and graft site management, radiation dermatitis and minor abrasions. Its popularity overseas has been for its. Clinical studies were conducted in the United States for burns, wound healing and radiation. Biafine is used to treat burns, skin irritations, superficial wounds and dryness. Its popularity overseas has been for its hydrating properties and effectiveness on sunburned skin and scrapes. Nighland says, "Absolutely not."ĭisclosure: Johnson & Johnson Consumer & Personal Products Worldwide fully sponsored this study.Biafine is used to treat burns, skin irritations, superficial wounds and dryness. When asked if there was anything surprising in the study's results, Ms. BIAFINE, emulsion for cutaneous application - TROLAMINE TROLAMINE - EMOLLIENTS AND PROTECTIVES - JOHNSON & JOHNSON Sante Beaute France 1 Rue camille. Researchers, therefore, concluded that physicians and patients can use the trolamine/sodium alginate emulsion to treat wounded skin without clinical concern for comedogenicity. However, the difference between these comedogenicity scores was not statistically significant (P ≤ 0.05). BIAFINE MOISTURIZING EMULSION PROMO Features: Indicated in case of burns, erythema and skin irritations. The active treatment posted a mean comedogenicity score of 0.65, versus 0.79 for the negative control. However, researchers did not perform a follicular biopsy on one subject who experienced overall irritation at the site of trolamine and sodium alginate occlusion, Ms. Most were Caucasian, and their mean age was 34 years. Nighland says.įourteen subjects - 13 female and one male - completed the study.
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Researchers considered samples with mean comedogenicity scores of one or more that were statistically greater than the mean value for negative control sites to be positive for comedogenicity, Ms. Researchers compared global assessment data for test and control sites, seeking statistically significant differences (P ≤ 0.05) using an analysis of variance (ANOVA) with pairwise comparisons (Fischer's least significant difference). Investigators graded microcomedone formation using the following global assessment scale: zero (no microcomedones), 0.5 (slight/1 percent to 24 percent smallish horny masses), one (slight/25 percent to 49 percent smallish horny masses), two (moderate/50 percent to 74 percent moderately sized horny masses) and three (severe/75 percent to 100 percent larger globoid microcomedones).
#Biafine emulsion Patch
Researchers then graded patch sites for irritation using the North American Contact Dermatitis Group rating scale.Īt the study's end, they also took follicular biopsies and examined the number and size of microcomedones present at each site. To serve as a negative control, researchers applied undosed occlusive patches to separate sites, which were randomized on a rotating basis for each patient. "Because no one would want to get comedone formation after they've just had their beautiful new skin revealed, we wanted to make sure that Biafine was noncomedogenic."įor the study, researchers recruited 15 healthy adult volunteers (ages 18 to 45 years) and applied the product to their upper backs, in areas where pores were clearly visible, a total of 12 times at 48- to 72-hour intervals under occlusive patches, Ms. approval, she says, "Many people were using the product after surgical procedures on their faces such as peels and laser treatments.